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 All Categories    Whatman Mini-UniPrep™ Syringeless Filters
All Categories > Filtration Products > Whatman Mini-UniPrep™ Syringeless Filters  

Whatman Mini-UniPrep™ Syringeless Filters

The Whatman Mini-UniPrep™ Syringeless Filters provide a faster and easier way to remove particulates from samples being prepared for High-Performance Liquid Chromatography (HPLC)/Ultra High Performance Liquid Chromatography (UHPLC) analysis. In fact, Whatman Mini-UniPrep lets you prepare samples in one third the time required by other methods. Add up the time savings, plus the money saved from cutting multiple consumables out of the sample preparation process and you'll see huge benefits for your laboratory.

Whatman Mini-UniPrep is a preassembled filtration device consisting of a 0.4mL capacity chamber and a plunger. The plunger contains a filtration membrane at one end and preattached cap/septum at the other. The plunger is pressed through the sample in the outer chamber and positive pressure forces the filtrate into the reservoir of the plunger. Air escapes through the vent holes until the locking ring is engaged providing an air-tight seal. Within seconds the Mini-UniPrep can be placed into your autosampler tray for injection into your instrument.

The device can be used either manually or with a compressor unit. The multi-compressor can process up to 6 samples at one time, further improving sample processing time and reducing the risk of hand stress. The Whatman Mini-UniPrep device is designed to fit into any autosampler accommodating 12x32mm vials. Alternatively, the septum can be pierced with a needle and the sample drawn off for manual injection into an analyzer.

Features and benefits

  • All-in-one filtration process allows you to process sample loads in one-third the time.
  • Wide Range of membrane choices from 0.2 and 0.45µm pore sizes to meet specific sample application requirements.
  • Compatible with most major autosamplers.
  • Fewer consumables required, reducing costs by up to 40%.


  • Routine HPLC/UHPLC analysis
  • Composite assays
  • Content uniformity
  • Protein precipitation
  • Solubility testing
  • Dissolution testing
  • Sample filtration

Amber Whatman Mini-UniPrep Syringeless Filter
Protects samples from UV damage.

Features and benefits

  • Amber colorant prevents photodegradation of light sensitive samples.
  • Same colorant used in pharmaceutical containers designed to meet USP specifications for light resistance.
  • Translucent amber chamber and plunger enable easy visual inspection.


  • Use with any compound that requires protection from light, such as catecholamines or vitamins.

Slit Septa Whatman Mini-UniPrep Syringeless Filter
For high-throughput automation.

Features and benefits

  • Slit septum cap enables Whatman Mini-UniPrep use with current robotics on HPLC instruments for high throughput automation.
  • Durable yet flexible slit septum cap has been specially designed for instruments with sensitive sampling needs.
  • Sample evaporation is minimal.


  • Use with standard robotics on HPLC instruments with sensitive needles, allowing for higher throughput.

Technical Specifications - 


Once compressed, equivalent in size to 12x32mm vial

Materials of Construction

Housing and Cap: Polypropylene
Filter Media: As specified
Septa: PTFE coated silicone rubber

Filtering Capacity


Nominal Force Needed to Compress

Approx. 18 lbs. (8.2 kg)

Maximum operating temperature

50°C (120°F)

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Nylon Filtration Media

Sample type: Aqueous/organic samples in 3 to 10 pH range

PVDF (Polyvinylidene Difluoride) Filtration Media

Sample type: Aqueous/organic solvents-low non-specific protein binding media

RC (Regenerated Cellulose) Filtration Media

Sample type: Aqueous/organic solvents-low non-specific protein binding media

PTFE (Polytetrafluoroethylene) Filtration Media

Sample type: Chemically aggressive solutions

PP (Polypropylene) Filtration Media

Sample type: General filtration media/solvent based samples

Depth PP (Polypropylene) Filtration Media

Sample type: Aqueous/organic solvents-high flow and loading capacity

GMF (Glass Microfiber) Filtration Media

Sample type: High particulate laden liquids

Accessories for Whatman Mini-UniPrep™ Syringeless Filters

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